The High-T CEO: Elite Bloodwork Blueprint.
The Definitive Guide to Accurate, Actionable Blood Testing for High-Performing Men Over 40.
Most leaders assume fatigue, brain fog, and fading drive are inevitable costs of success.
They're wrong.
These are symptoms of biological mismanagement.
They're rooted in flawed data, outdated ranges, and corporate lab protocols built for billing, not performance.
Conventional blood tests miss critical biomarkers.
They hide dysfunction behind “normal” ranges. They waste your time with false clarity and vague advice.
This guide is your hormonal home base for unlocking true biological sovereignty.
Inside, you'll discover:
The exact biomarkers every leader must track to sustain focus, vitality, and libido
The 4 deadly pitfalls of standard blood tests that silently destroy testosterone
Elite lab recommendations that use gold-standard methods (LC-MS/MS, Equilibrium Dialysis, intracellular nutrient testing)
A quarterly executive testing schedule to keep your biology weaponized
Interpretation principles that convert labs into power (not confusion)
If you want clarity, not confusion… I strongly encourage you to read every word.
Why?
Because your biology is your power and you need to protect it like your business depends on it (because it does).
Why Bloodwork Accuracy Matters.
Let me just start by emphasising:
This is not a standard wellness pamphlet. This is your hormonal war plan.
You know as well as I do… you don’t build a $10M business using bad data.
So don’t build your body that way either.
The biggest mistake I see most men make is thinking their low energy, poor sleep, and fading drive are due to age.
They're not.
They're the result of inaccurate tests, misunderstood ranges, and lazy diagnostics.
Doctors tell you “everything looks normal” while your testosterone tanks and your focus and drive evaporates.
Because they’re not looking in the right place.
Because they’re using the wrong tests.
Because in most cases, their goal is liability, not optimization.
My hope is that this blueprint changes that (feedback has been great so far, so I really do hope you get value too).
Common Pitfalls and Misunderstandings.
Why Most Men Are Operating on False Data and Paying the Price.
Pitfall #1: Trusting Standard Labs (LabCorp, Quest, Walk-In Clinics).
These labs use outdated, insurance-driven methods that focus on speed over precision.
Free Testosterone, SHBG, and RT3 are measured via immunoassay (±30% error)
Micronutrients are measured in serum (reflecting recent intake, not actual use)
Why it matters:
You’ll be told your testosterone is “fine” when it’s functionally useless.
You’ll think you’re nutritionally replete while your mitochondria starve.
You know as well as I do, it doesn’t take a rocket scientist to realize that garbage data = garbage decisions.
Pitfall #2: Relying on Blood Tests Alone.
Blood shows what’s circulating in the moment.. not how your body uses, clears, or detoxes it.
Saliva reveals your diurnal cortisol rhythms (more accurately than blood)
Urine reveals hormone detox capacity (more accurately than blood)
Hair reveals long-term heavy metal toxicity (more accurately than using blood alone)
Why it matters:
You can have perfect Total Testosterone and still feel flatlined because you're recycling estrogen or your adrenals are shot.
Don’t make the same mistake as my former self…
You need more than blood to see a clear picture of your hormonal battlefield.
Pitfall #3: Technical Errors That Ruin Data.
Even good tests become worthless when executed poorly.
SST gel tubes degrade steroid hormones
Tourniquets >30 seconds cause hemolysis
Non-fasted bloodwork skews insulin, glucose, and triglycerides
Why it matters:
One technical mistake can ruin $1,000 of testing. And worse... you won’t even know it.
Back in 2018, I had a blood test show I had ZERO testosterone.
If it wasn’t for my fierce insistence to get it retested to check it wasn’t an anomaly, I’d be dependent on TRT right now (which I’m not, thank God).
Pitfall #4: Using “Normal” Ranges Instead of Functionally Optimal Ranges.
Lab reference ranges reflect the average population, not truly optimized men.
A Total Testosterone of 300 ng/dL is “normal” in the modern population.
But in practice?
It’s flatline mode for ambitious men. The same goes for other bio-markers like TSH, LDL, HDL, and Vitamin D.
Why it matters:
You’ll walk out of the clinic thinking you’re fine. But in reality?
You’re not fine. You’re decaying with paperwork that says otherwise.
Optimal Testing Methods and Biomarkers.
These are the Precision Tools of High-T Executives.
You don’t need more labs. You need better ones. Here’s what to test, why it matters, and what each method actually reveals.
Method 1: Blood (Serum LC-MS/MS Only)
Best for:
Testosterone (Total + Free)
Estradiol
SHBG
LH, FSH
Prolactin
Vitamin D
Reverse T3
Cholesterol, Albumin, Liver Enzymes
Why it matters:
LC-MS/MS provides ±2–5% precision. Immunoassay provides ±25–30%.
The former gives you actionable data. The latter gives you false certainty.
Method 2: Saliva (Cortisol Rhythm, DHEA)
Best for:
Adrenal patterns
Cortisol rhythm (How it changes from waking to bedtime)
Stress-load insight
Why it matters:
Blood can’t track rhythm and it generally only measures what’s bound to proteins.
Saliva reveals the amount of free (unbound) cortisol and DHEA levels you have in your body (which is the important, usable form)..
And saliva helps with understanding if you’re spiking cortisol at night, flatlining in the morning, or crashing midday...
All of which sabotage testosterone, sleep and ultimately your performance.
Method 3: Urine (Dutch or Organic Acids).
Best for:
Hormone detox pathways (Phase I + II)
Estrogen metabolite load
Methylation efficiency
Mitochondrial resilience
Why it matters:
Blood tells you what you’re producing.
Urine tells you how you’re using it and whether you're building power or recycling dysfunction.
Method 4: Hair Mineral Analysis.
Best for:
Long-term heavy metal toxicity (lead, mercury, cadmium)
Mineral status
Detox resistance indicators
Why it matters:
If you’re inflamed, anxious, or stuck in recovery limbo...
Heavy metals are a silent killer (it’ll shock you just how ubiquitous they are and the kind of places you find them).
Blood misses them but hair shows the truth (to a large extent, it’s still not perfect though).
Executive Biomarker Targets.
You Don’t Aim for Normal. You Aim for Power (Optimal Ranges).
These are just a few of the most important biomarkers (there’re more) so if there’s one missing there that you’d like me to add or comment on, leave a comment below.
Elite US Lab Providers.
Where to Test Without Sabotaging the Results.
Access Medical Labs
Method: LC-MS/MS, Equilibrium Dialysis
Use For: Testosterone, Estradiol, SHBG, RT3, Prolactin
Why: Direct, precision data. Used by elite functional clinics.
Dutch Complete (Precision Analytical)
Method: Saliva + Urine
Use For: Cortisol rhythm, hormone detox, methylation, DHEA
Why: Combines adrenal insight with hormone clearance pathways in a single view.
ZRT Labs
Method: Fingerstick + LC-MS/MS
Use For: FT3, FT4, RT3, TPO
Why: At-home precision for thyroid panels without phlebotomy errors.
SpectraCell
Method: Intracellular (lymphocyte proliferation)
Use For: Magnesium, Zinc, B12, Selenium, Folate
Why: Reveals what your cells actually absorb, not just what’s floating in blood.
Cleveland HeartLab (via Quest)
Method: Advanced inflammatory screening
Use For: CRP, Homocysteine, GGT, ALT/AST
Why: Cardiometabolic stress is the silent testosterone killer.
Your Strategic Bloodwork Schedule.
Quarterly Command Cycles for Biological Dominance.
You don’t check your P&L once a year so why would you audit your biology any differently?
Every 90 Days (Hormone & Inflammation Panel)
Free T, Total T, SHBG, Estradiol
LH, FSH, Prolactin
FT3, FT4, RT3, TSH
Lipids, Albumin, CRP, Homocysteine
Every 6 Months (Micronutrient & Detox Panel)
Intracellular Mg, Zn, B12, Folate, Selenium (SpectraCell)
ALT, AST, GGT, Bilirubin
Every 12 Months (Adrenal & Hormone Clearance)
Dutch Complete
Cortisol rhythm
DHEA-S
Estrogen/Testosterone metabolite clearance
Methylation and detox markers
Interpretation and Action Framework.
Read Labs Like a CFO Reads a Balance Sheet.
1. Don’t trust "normal"… aim for optimal.
If your Testosterone is 350 and your doc says “you’re fine,” fire him. You’re not fine. You’re declining.
2. Recognize patterns, not just red flags.
Low Free T + High SHBG = low bioavailable testosterone
Normal TSH + low FT3 + high RT3 = thyroid resistance
High Prolactin + low drive = dopamine system crash
(Of course, there’re more examples than this. If you want me to comment on any specific to you, feel free to comment below)
3. Act on cause, not just symptoms
Don’t patch low T with TRT
Find out why your pituitary or thyroid isn’t signalling properly (RHR & body temperature can be key here)
Fix your adrenals (salts and unpasteurized juices and milks are underestimated here)
Balance your methylation (organ meats are often overlooked here)
Open detox pathways (liver function is key here)
Support mitochondrial energy (light and grounding are underrated here)
You now hold the blueprint. Most men ignore it and will erode silently.
Do not be most men.
You pride yourself as being a leader (so act like one).
This isn’t about tracking numbers…
This is about dominating your biology so it never dominates you.
This is about protecting your longevity so you feel like 50 at 70.
So order the labs…
Make sure you track with precision (and get the right advice to interpret them)…
And then act with power and conviction (like you do in your business).
I don’t need to remind you that without your health and virility, you have nothing.
Don’t do this for you.. do this for your wife, your kids and for those in your business.
Because that’s what real masculinity is..
It’s taking full responsibility and using our virility to serve with integrity so others around us feel safe and secure.
That’s it.
I really do hope this added value.
See you next time.
— Simmo.
P.S.
Whenever you’re ready, here’re 3 ways I can help you…
Apply to work with me 1-on-1 here:
Join the waitlist for my up-and-coming release of the High-T CEO Operating System here:
Comment below with “Good” and restack it so others, like you, can benefit from the value of my work:
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Disclaimer: This content is for informational and entertainment purposes only and is not medical, nutritional, fitness, or professional health advice. I, Tom Simmons, am not a licensed healthcare professional; all information reflects personal opinions or general knowledge, not expert recommendations. Consult a qualified physician, dietitian, or licensed professional before making health-related changes. Use of this content is at your own risk. Tom Simmons is not liable for any adverse effects or consequences arising from its use, including but not limited to injury or health complications. By using this content, you agree to this disclaimer. For personalized advice, seek a certified professional.





This is gold Simmo. Most ‘normal’ ranges are benchmarked against the data accumulated by reporting sick people’s results and do not consider optimal. In Aus, government advised ( and therefore funded) ranges are calibrated on the lowest values that will make you sick.
I would add HbA1C and perhaps other insulin markers.